Heat the oven to 350 degrees.
Spray a skillet with cooking spray and saute the onions and peppers until softened.
Add the chicken, soup, Rotel, chili powder, garlic powder and pepper to taste to the vegetable mixture. Stir to combine.
Layer ⅓ of the tortilla pieces in the bottom of a well greased 9x9 baking dish.
Top with ⅓ of the chicken mixture.
Create another layer of tortilla pieces and then another third of the chicken.
Finish with a third layer of tortilla pieces and the remaining chicken mixture.
Top with the cheese and bake for 30-35 minutes.
Enjoy!