Preheat the oven to 400°F.
Stir the mustard, relish and mayonnaise together.
Stir in the onion powder, garlic powder, salt, and black pepper.
Heat some oil in a skillet and add the beef.
Cook it, breaking it up with a wooden spoon.
Add the onions and, once everything is cooked, drain the excess grease.
Mix in the salt, pepper, onion powder, and garlic powder.
Add the water and cook until all the water is gone.
Take the mixture off the heat.
Use parchment paper to line a baking sheet.
Cut the sub rolls open and put them on the baking sheet.
Spread the sauce on top then add the ground beef mixture on the bottoms.
Add cheddar cheese on top of the beef.
Put the bun tops back on.
Bake for 6 minutes or until the cheese melts.
Open and add lettuce and tomato slices if desired.
Close back up and serve.